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Patent

Phosphoramidate derivatives of 5-fluoro-2′-deoxyuridine for use in the treatment of cancer

Phosphoramidate derivatives of 5-fluoro-2′-deoxyuridine are disclosed for use in the treatment of cancer, especially in the treatment of cancer where the patient shows resistance, for example, in a patient with cells with a lowered level of nucleoside transporter proteins and/or with nucleoside kinase-deficient cells and/or with mycoplasma-infected cells and/or with cells with a raised level of thymidylate synthase.
Patent Publication Number: US9221866
Year filing: 2014
Year approval: 2015
Year publication: 2015
Status: Assigned
Technology domains: Pharmaceuticals
Validated for IOF-key: Yes
Attributed to: Associatie KULeuven