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Patent

Oxidative stress and cardiovascular disease events

The present invention relates to diagnosis and/or prognosis of cardiovascular disease and cardiovascular events. A prognostic risk score in relation to the cardiovascular events, more particular after intervention, can be determined by counting the number of deregulated genes (or derived proteins) in their isolated monocytes. Deregulation means low expression of COX1 and/or COX4/1, and/or TFAM, and/or RUNX2.
Patent Publication Number: EP3110973
Source: EPO
Year filing: 2015
Year approval: 2019
Year publication: 2019
Status: Assigned
Technology domains: Biotechnology
Validated for IOF-key: Yes
Attributed to: Associatie KULeuven