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Patent

Mutant microorganisms to synthesize colanic acid and/or fucosylated oligosaccharides

By knocking out two regulatory genes in E. coli (arcA and iclR), the colanic acid operon is upregulated. This leads in the biosynthesis of GDP-fucose, a precursor of fucosyllactose.
Patent Publication Number: US20140349348
Source: USPTO
Year filing: 2012
Year approval: 2017
Year publication: 2017
Status: Assigned
Technology domains: Biotechnology
Validated for IOF-key: Yes