Cooperia vaccine

Cooperia oncophora is a pathogenic nematode species parasitizing the small intestines of cattle. In temperate climate regions, co-infections of C. oncophora species with other gastrointestinal parasites such as Ostertagia ostertagi cause important production losses. The control of these helminth infections relies heavily on the use of broad-spectrum anthelmintics such as the macrocyclic lactones, benzimidazoles and levamisole. However, intensive use of these drugs has led to the development of resistance in livestock parasites against all anthelmintic classes. The present inventors identified two antigen fractions purified from the excretory/secretory material of adult C. oncophora worms which elicit a protective immune response in calves against a C. oncophora challenge infection.

Patent Publication Number: EP2906588

Year filing: 2018

Year approval: 2018

Year publication: 2018

Status: Assigned

Technology domains: Biotechnology

Validated for IOF-key: Yes

Attributed to: Associatie Universiteit Gent