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Colon cancer

The present invention relates generally to a method of predicting clinical outcome in a subject diagnosed with colorectal cancer comprising determining evidence of a miRNA profile or the expression of one or more predictive RNA transcripts in a biological sample, in particular a biological sample of cancer cells obtained from the subject. It further concerns using the profile a prognostic miRNA signature for relapse-free survival (RFS) in prognosis of a patient for colorectal cancer, in particular stage III colon cancer, and recurrence or response to therapy for colon cancer, in particular stage III colon cancer.
Patent Publication Number: WO2016115609
Year filing: 2016
Year approval: 2017
Year publication: 2016
Status: Requested
Technology domains: Biotechnology
Validated for IOF-key: Yes
Attributed to: Associatie KULeuven