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Organisation

Toxicology and Pharmacology

Division

Lifecycle:1 Jul 1977  →  Today
Organisation profile:

The lab of Toxicology and Pharmacology consists of two main research fields: Forensic Toxicology and Drug Discovery and Pharmacology.

The research objectives of Forensic Toxicology are focused on optimization of analytical detection methods/tools and volatile decomposition detection. The main practice of this subdivision is its service in juridical dossiers as expertise and investigation center at the request of the Ministry of Justice.

The research objectives of Drug Discovery and Pharmacology are mainly focused on investigation of venom from poisonous/venomous animals such as spiders, sea-anemones, cone snails, scorpions, cnidaria etc. Because these venom peptides regularly work on ion channels of the human body, they are interesting lead compounds for the development of f.e. analgetics, anti-cancer drugs, drugs for neurological disorders such as multiple sclerosis, Parkinson’s disease or Alzheimer’s disease, etc.

- Determination of xenobiotics in biological specimens. - Purification and characterization of peptide toxins from plant, animal and microbial organisms. - Structure-function studies of membrane-bound receptors and ion channels.

Keywords:Toxicology, Pharmacology
Disciplines:Biomarker discovery and evaluation, Drug discovery and development, Medicinal products, Pharmaceutics, Pharmacognosy and phytochemistry, Pharmacology, Pharmacotherapy, Toxicology and toxinology, Other pharmaceutical sciences