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Organisation

Switch Laboratory (VIB-KU Leuven Center for Brain & Disease Research)

Division

Lifecycle:1 Jan 2011  →  Today
Organisation profile:

Our research is focused on understanding the mechanisms gearing protein folding and misfolding and their relation to human disease. In particular we are investigating how protein aggregation affects the cellular interactome by suppressing native interactions but also by introducing novel aggregation-specific interactions. The latter are especially relevant as they are usually associated to gain of function activities such as neurotoxicity (neurodegeneration) or cell proliferation (cancer).

Keywords:Switch Laboratorium
Disciplines:Laboratory medicine, Palliative care and end-of-life care, Regenerative medicine, Other basic sciences, Other health sciences, Nursing, Other paramedical sciences, Other translational sciences, Other medical and health sciences