Structural Biology Brussels (SBBV)
The Structural Biology Brussels Lab, headed by Jan Steyaert was founded by Lode Wyns in the seventies at the Vrije Universiteit Brussel and is one of the Flanders Institute for Biotechnology departments. The understanding of the function of a protein, from its structure to its dynamics, remains the central theme of the lab. Our multidisciplinary team of about 40 researchers is housed in new laboratory facilities and combines extensive expertise in biophysics and molecular biology. We master genetic engineering, protein purification, enzymology, calorimetry, crystallography, surface plasmon resonance, atomic force microscopy and now also NMR. Major esearch interests include Aggregating proteins and Amyloidosis, Membrane proteins, Protein assemblies, Redox regulation, RNA modification, Nanomodulators, Cell surface fillaments & Adhesion, Urinary tract infections, Enterotoxigenic E. coli, Molecular reognition and Toxin-Anti Toxin systems. Translational research is intrinsic to our programs, with possible applications in medicine.