Organisation
Laboratory for Tumor Microenvironment and Therapeutic Resistance (VIB-KU Leuven)
Division
Interaction of the tumor microenvironment and tumor cell compartment Tumor niches and therapeutic resistance Resistance to antiangiogenic therapy Vascular and immunomodulation in cancer
Current researchers
1 - 7 of 7 results
- Gabriele Bergers (Responsible)
- Gabriele Bergers (Member)
- Ana Filipa Domingues Laranjeiro (Member)
- Mélanie Guyot (Member)
- Dorothy John Robbert (Member)
- Pieter Maene (Member)
- Jenny Weng (Member)
Projects
1 - 10 of 24
- Targeting the Treg – macrophage axis to promote immune stimulation and tertiary lymphoid structure formation in IDHwt GBM TME subtypesFrom25 Aug 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Exploring the role of vascular remodeling in premetastatic and metastatic lymph nodesFrom25 Jan 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Unique IsoPlexis technology for multiplexed single cell functional profilingFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- Golden-NK: employing gold-mediated thermal heating for improved and safe immunotherapyFrom1 Oct 2022 → TodayFunding: BOF - projects
- Imaging the invisible in preclinical models using magnetic particle imagingFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Understanding and tackling the spatio-temporal changes of the metastatic lymph node epicenterFrom1 Jan 2022 → TodayFunding: FWO EOS
- Immune functions and regulation of high-endothelial venulesFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- ACTIVATE: Autophagy is a master regulator for the immune funCTions of the lymph node VasculATurEFrom1 Oct 2021 → TodayFunding: FWO junior postdoctoral fellowship
- Exploring the reciprocal crosstalk between the vasculature in cancer to improve immunotherapyFrom15 Feb 2021 → TodayFunding: FWO fellowships, Foundations, funds and other with scientific goal
Publications
11 - 20 of 38
- Peptide-guided nanoparticles for glioblastoma targeting(2019)
Authors: Gabriele Bergers
Pages: 109 - 118 - A tension-mediated glycocalyx-integrin feedback loop promotes mesenchymal-like glioblastoma(2018)
Authors: Gabriele Bergers
Pages: 1203 - + - LGL1 binds to Integrin 01 and inhibits downstream signaling to promote epithelial branching in the mammary gland(2022)
Authors: Gabriele Bergers
- Combined antiangiogenic and anti-PD-L1 therapy stimulates tumor immunity through HEV formation(2017)
Authors: Inge Lodewijckx, Gabriele Bergers
- Tumor endothelial cell autophagy is a key vascular-immune checkpoint in melanoma(2023)
Authors: Francesca Rizzollo, Johan Van Weyenbergh, Oliver Bechter, Francesca Bosisio, Diether Lambrechts, Gabriele Bergers, Patrizia Agostinis
- How high endothelial venules support anti-tumoral immunity in cancer(2023)
Authors: Gerlanda Vella, Gabriele Bergers
- Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loop(2022)
Authors: Yichao Hua, Gerlanda Vella, Ann Smeets, David Nittner, Francesca Bosisio, Beppe Floris, Diether Lambrechts, Chris Marine, Susan Schlenner, Gabriele Bergers
Pages: 1600 - + - Multiomics and spatial mapping characterizes human CD8+T cell states in cancer(2023)
Authors: Stefan Naulaerts, Daniel Borras Morales, Julie Messiaen, Isaure Vanmeerbeek, Jenny Sprooten, Dena Panovska, Yannick Van Herck, Lendert Gelens, Tom Venken, Oliver Bechter, et al.
- IDENTIFICATION OF A NOVEL TYROSINE KINASE/INTEGRIN COMPLEX THAT DRIVES BRAIN METASTASES(2017)
Authors: Arman Jahangiri, Maxim Sidorov, Alan Nguyen, Garima Yagnik, Sung Won Han, Smita Mascharak, Michael De Lay, Jeffrey Wagner, Brandyn Castro, Brandon Imber, et al.
Pages: 24 - 24 - High endothelial venules in cancer: Regulation, function, and therapeutic implication(2023)
Authors: Yichao Hua, Gabriele Bergers
Pages: 527 - 545