Organisation
Laboratory for Tumor Microenvironment and Therapeutic Resistance (VIB-KU Leuven)
Division
Interaction of the tumor microenvironment and tumor cell compartment Tumor niches and therapeutic resistance Resistance to antiangiogenic therapy Vascular and immunomodulation in cancer
Current researchers
1 - 7 of 7 results
- Gabriele Bergers (Responsible)
- Gabriele Bergers (Member)
- Ana Filipa Domingues Laranjeiro (Member)
- Mélanie Guyot (Member)
- Dorothy John Robbert (Member)
- Pieter Maene (Member)
- Jenny Weng (Member)
Projects
1 - 10 of 24
- Targeting the Treg – macrophage axis to promote immune stimulation and tertiary lymphoid structure formation in IDHwt GBM TME subtypesFrom25 Aug 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Exploring the role of vascular remodeling in premetastatic and metastatic lymph nodesFrom25 Jan 2023 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Unique IsoPlexis technology for multiplexed single cell functional profilingFrom1 Jan 2023 → TodayFunding: BOF - scientific equipment program
- Golden-NK: employing gold-mediated thermal heating for improved and safe immunotherapyFrom1 Oct 2022 → TodayFunding: BOF - projects
- Imaging the invisible in preclinical models using magnetic particle imagingFrom1 May 2022 → TodayFunding: FWO Large scale research infrastructure
- Next-generation, multi-technology immune-monitoring and easy-access spectral flow cytometryFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Understanding and tackling the spatio-temporal changes of the metastatic lymph node epicenterFrom1 Jan 2022 → TodayFunding: FWO EOS
- Immune functions and regulation of high-endothelial venulesFrom1 Jan 2022 → TodayFunding: FWO research project (including WEAVE projects)
- ACTIVATE: Autophagy is a master regulator for the immune funCTions of the lymph node VasculATurEFrom1 Oct 2021 → TodayFunding: FWO junior postdoctoral fellowship
- Exploring the reciprocal crosstalk between the vasculature in cancer to improve immunotherapyFrom15 Feb 2021 → TodayFunding: FWO fellowships, Foundations, funds and other with scientific goal
Publications
1 - 10 of 38
- GAINING A MECHANISTIC UNDERSTANDING OF THERAPY EVASION FROM DUAL MAPK PATHWAY INHIBITION IN A SYNGENEIC BRAFV600E MUTANT CDKN2A DELETED MOUSE MODEL'TO PREEMPT RESISTANCE IN PATIENTS WITH BRAFV600E MUTANT E PEDIATRIC ClIOMA(2019)
Authors: Wei Wang, Stefan Grossauer, Katharina Koeck, Erin Simonds, Edbert Lu, Gabriele Bergers, William Weiss, Claudia Petritsch
Pages: 121 - 122 - Glioblastoma: To Target the Tumor Cell or the microenvironment?(2018)
Authors: Steven De Vleeschouwer, Gabriele Bergers
Pages: 315 - 340 - Phenotypes and genotypes of Chinese adult patients with systemic autoinflammatory diseases(2019)
Authors: Yichao Hua
Pages: 446 - 452 - A cellular hierarchy in melanoma uncouples growth and metastasis (vol 610, pg 190, 2022)(2022)
Authors: Panagiotis Karras, Joanna Poźniak, Nina Van Raemdonck, Ewout Landeloos, Yannick Van Herck, Michael Dewaele, Yichao Hua, Gabriele Bergers, Francesca Bosisio, Joost van den Oord, et al.
Pages: E4 - E4 - Adaptive immunosuppressive resistance mechanisms towards antiangiogenic immunotherapies revealed in a pancreatic neuroendocrine tumor (PNET) model(2023)
Authors: Chris Verslype, Diether Lambrechts, Gabriele Bergers
Pages: 26 - 26 - Where Have All the T Cells Gone?(2018)
Authors: Gerlanda Vella, Gabriele Bergers
Pages: 592 - 594 - Lipid droplet degradation by autophagy connects mitochondria metabolism to Prox1-driven expression of lymphatic genes and lymphangiogenesis(2022)
Authors: Diede Houbaert, Maria Livia Sassano, Mila Borri, Jelle Verhoeven, Madhur Agrawal, Gabriele Bergers, Bart Ghesquière, Mieke Dewerchin, Johan Swinnen, Peter Carmeliet, et al.
- GBM tumors are heterogeneous in their fatty acid metabolism and modulating fatty acid metabolism sensitizes cancer cells derived from recurring GBM tumors to temozolomide(2022)
Authors: Steven De Vleeschouwer, Raf Sciot, Jenny Weng, Francesca Bosisio, Gabriele Bergers, Frederik De Smet, Diether Lambrechts, Sarah-Maria Fendt
- A CROSS-ACTIVATING c-Met/beta 1 INTEGRIN COMPLEX DRIVES THERAPEUTIC RESISTANCE IN GLIOBLASTOMA(2016)
Authors: Arman Jahangiri, Maxim Sidorov, Sung Won Han, William Chen, Jonathan Rick, Dina Schneidman-Duhovny, Smita Mascharak, Michael De Lay, Jeffrey Wagner, Brandyn Castro, et al.
Pages: 53 - 54 - Autophagy dysfunction in autoinflammatory diseases(2018)
Authors: Yichao Hua
Pages: 11 - 20