Organisation
Laboratory of Tumor Inflammation and Angiogenesis (VIB-KU Leuven)
Division
The Lab of Molecular Oncology and Angiogenesis aims to shed light on the genetic and molecular mechanisms that regulate vessel shape remodeling and endothelial cell fate, with the overall aim of defining alternative therapeutic opportunities to improve anti-cancer therapy, as well as therapeutic angiogenesis for revascularization of ischemic tissues.
Projects
51 - 60 of 69
- The neurovascular link: an unexpectedly important role of metabolism.From1 Oct 2014 → 30 Sep 2021Funding: BOF - Methusalem
- GLUD1 inhibition promotes macrophage-mediated glutamine release, enhancing satellite cell activation and muscle regenerationFrom2 Sep 2014 → 20 Jun 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
- Assessing the influence of weight and nutrition on recovery and quality of life after esophagectomy for cancerFrom1 Sep 2014 → 1 Jun 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Identification of candidate biomarkers of intrinsic and acquired resistance to anti-angiogenic agents in metastatic colorectal cancer.From1 Jan 2013 → 31 Dec 2014Funding: Private funding of national origin - undefined
- Unraveling the role of Neuropilin 1 in tumor-associated macrophages : implications for therapy.From1 Jan 2013 → 31 Dec 2016Funding: FWO research project (including WEAVE projects)
- The development of a proteomics procedure for the analysis of formalin-fixed paraffin-embedded tissue with the purpose of use in clinical studies.From1 Oct 2012 → 31 Dec 2017Funding: IWT personal funding - strategic basic research grants, BOF - Doctoral projects
- Role of PHD2 in cancer: PBP1 as new hub in the understanding of hypoxia driven-tumorigenesis.From1 Oct 2012 → 30 Sep 2015Funding: FWO fellowships
- Wordkstation for high speed and resolution imaging of living animals by confocal multiphoton laser scanning microscopy.From28 Jun 2012 → 27 Dec 2018Funding: Hercules - Small and Medium size research infrastructure
- Unraveling new molecular pathways in the oxygen sensing machinery.From1 Jan 2012 → 31 Dec 2015Funding: FWO research project (including WEAVE projects)
- The role of PHD mediated suppression of NF-kB signaling in tumor inflammation.From1 Oct 2011 → 5 Feb 2017Funding: FWO fellowships
Publications
1 - 10 of 314
- Evolution of the Experimental Models of Cholangiocarcinoma(2020)
Authors: Chiara Varamo
- Insulin potentiates FcepsilonRI-mediated signaling in mouse bone marrow-derived mast cells(2010)
Authors: Mario di Matteo
Pages: 1039 - 1046 - In vivo antitumoral efficacy of PhAc-ALGP-doxorubicin, an enzyme-activated doxorubicin prodrug, in patient-derived soft tissue sarcoma xenograft models(2017)
Authors: Jasmien Cornillie, Agnieszka Wozniak, Peter Pokreisz, Andrea Casazza, Yemarshet Kelemework Gebreyohannes, Maria Debiec-Rychter, Raf Sciot, Daphne Hompes, Patrick Schöffski
Pages: 1566 - 1575 - microRNAs in ES Cell Differentiation(2012)
Authors: Emanuele Berardi, Lieven Thorrez, Maurilio Sampaolesi
Pages: H931 - H939 - Podoplanin-Expressing Macrophages (PoEMs) Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer(2019)
Authors: Pawel Jacek Bieniasz-Krzywiec, Max Mazzone
- PRO-INVASIVE TUMOUR-STROMA INTERACTIONS: ROLE OF THE SECRETED OXIDOREDUCTASE CLIC3(2019)
Authors: Juan R Hernandez-Fernaud, Elena Ruengeler, Lisa J Neilson, Shehab Ismail, Iain McNeish, Samuel Atkinson, Sergio Lilla, Alice Santi, Stella M Valenzuela, Karen Blyth, et al.
Pages: 136 - 136 - Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling(2019)
Authors: Shehab Ismail Mohamed, Max Mazzone
- Identification of a chronic non-neurodegenerative microglia activation state in a mouse model of peroxisomal β-oxidation deficiency(2015)
Authors: Simon Verheijden, Lien Beckers, Andrea Casazza, Oleg Butovsky, Max Mazzone, Myriam Baes
Pages: 1606 - 20 - Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment(2014)
Authors: Andrea Casazza, Giusy Di Conza, Mathias Wenes, Veronica Finisguerra, Sofie Deschoemaeker, Max Mazzone
Pages: 1743 - 1754 - Tumour growth inhibition and anti-metastatic activity of a mutated furin-resistant Semaphorin 3E isoform(2012)
Authors: Andrea Casazza, Max Mazzone
Pages: 234 - 50