Organisation
Laboratory of Tumor Inflammation and Angiogenesis (VIB-KU Leuven)
Division
The Lab of Molecular Oncology and Angiogenesis aims to shed light on the genetic and molecular mechanisms that regulate vessel shape remodeling and endothelial cell fate, with the overall aim of defining alternative therapeutic opportunities to improve anti-cancer therapy, as well as therapeutic angiogenesis for revascularization of ischemic tissues.
Projects
31 - 40 of 69
- A metabolic gene survey pinpoints fucosylation as a key pathway underlying the suppressive function of Regulatory T cells in cancer.From21 Sep 2017 → 16 May 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancerFrom4 Sep 2017 → 26 Jan 2023Funding: Foundations, funds and other with scientific goal
- Exploring strategies to reduce toxicity in the multimodal treatment of esophageal cancerFrom1 Jun 2017 → 31 May 2021Funding: Nonprofit institution or equivalents
- A comparative clinical study of a stool-based versus a blood-based screening test for earlydetection of CRCFrom1 Apr 2017 → 30 Sep 2018Funding: Own budget, for example: patrimony, inscription fees, gifts
- Role of Ketone bodies in muscle anabolism and catabolism during exercise and trainingFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Role of the PP2A regulatory subunit B55α in tumor stromal cells and its validation as a potential target to inhibit cancer progressionFrom1 Jan 2017 → 31 Dec 2018Funding: Private funding of national origin - undefined
- Metabolism following function or function following metabolism: a study of AMPK in tumor-associated macrophagesFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- Exploring the role of TRAIL pathway in the tumor stroma: implications for cancer progression and drug resistanceFrom1 Jan 2017 → 31 Dec 2020Funding: FWO research project (including WEAVE projects)
- AMPK: a master switch integrating metamoblism and immune effector functions in tumor-associated macrophagesFrom1 Oct 2016 → 30 Sep 2020Funding: FWO fellowships
- Exploring how TAMs hijack the TRAIL system to fuel tumor progression and drug resistanceFrom1 Oct 2016 → 22 May 2023Funding: FWO fellowships
Publications
1 - 10 of 311
- Evolution of the Experimental Models of Cholangiocarcinoma(2020)
Authors: Chiara Varamo
- Insulin potentiates FcepsilonRI-mediated signaling in mouse bone marrow-derived mast cells(2010)
Authors: Mario di Matteo
Pages: 1039 - 1046 - In vivo antitumoral efficacy of PhAc-ALGP-doxorubicin, an enzyme-activated doxorubicin prodrug, in patient-derived soft tissue sarcoma xenograft models(2017)
Authors: Jasmien Cornillie, Agnieszka Wozniak, Peter Pokreisz, Andrea Casazza, Yemarshet Kelemework Gebreyohannes, Maria Debiec-Rychter, Raf Sciot, Daphne Hompes, Patrick Schöffski
Pages: 1566 - 1575 - microRNAs in ES Cell Differentiation(2012)
Authors: Emanuele Berardi, Lieven Thorrez, Maurilio Sampaolesi
Pages: H931 - H939 - Metabolic traits ruling the specificity of the immune response in different cancer types(2021)
Authors: Federica Cappellesso, Samantha Pretto, Max Mazzone
Pages: 124 - 143 - Podoplanin-Expressing Macrophages (PoEMs) Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer(2019)
Authors: Pawel Jacek Bieniasz-Krzywiec, Max Mazzone
- PRO-INVASIVE TUMOUR-STROMA INTERACTIONS: ROLE OF THE SECRETED OXIDOREDUCTASE CLIC3(2019)
Authors: Juan R Hernandez-Fernaud, Elena Ruengeler, Lisa J Neilson, Shehab Ismail, Iain McNeish, Samuel Atkinson, Sergio Lilla, Alice Santi, Stella M Valenzuela, Karen Blyth, et al.
Pages: 136 - 136 - Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling(2019)
Authors: Shehab Ismail Mohamed, Max Mazzone
- Identification of a chronic non-neurodegenerative microglia activation state in a mouse model of peroxisomal β-oxidation deficiency(2015)
Authors: Simon Verheijden, Lien Beckers, Andrea Casazza, Oleg Butovsky, Max Mazzone, Myriam Baes
Pages: 1606 - 20 - Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment(2014)
Authors: Andrea Casazza, Giusy Di Conza, Mathias Wenes, Veronica Finisguerra, Sofie Deschoemaeker, Max Mazzone
Pages: 1743 - 1754