Organisation
Laboratory of Tumor Inflammation and Angiogenesis (VIB-KU Leuven)
Division
The Lab of Molecular Oncology and Angiogenesis aims to shed light on the genetic and molecular mechanisms that regulate vessel shape remodeling and endothelial cell fate, with the overall aim of defining alternative therapeutic opportunities to improve anti-cancer therapy, as well as therapeutic angiogenesis for revascularization of ischemic tissues.
Projects
21 - 30 of 69
- Exploring the role of PlexinA4 en cytotoxic T cells: insights for anti-tumor immune responses and cancer immunotherapyFrom1 Oct 2019 → 30 Sep 2023Funding: Foundations, funds and other with scientific goal
- Exploring mechanisms of immunotherapy resistance in pancreatic cancerFrom3 May 2019 → 16 Feb 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- Integrated IMMUnoprofiling of large adaptive CANcer patients cohortsFrom1 Mar 2019 → TodayFunding: H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and wellbeing, H2020 - European Institute of Innovation and Technology
- Exploring the role of PlexinA4 in cytotoxic T cells: insights for antitumor immune response & cancer immunotherapyFrom1 Feb 2019 → 31 Oct 2023Funding: FWO fellowships, Foundations, funds and other with scientific goal
- Metabolic editing of the tumor microenvironment as a novel strategy to abate immunosuppressionFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Exploring the role of PlexinA4 in cytotoxic T cells: insights for antitumor immune response & cancer immunotherapyFrom1 Jan 2019 → 31 Dec 2022Funding: FWO research project (including WEAVE projects)
- Harnessing tumor metabolism to overcome immunosupressionFrom1 Jul 2018 → 30 Jun 2023Funding: Own budget, for example: patrimony, inscription fees, gifts
- Mass cytometry by time-of-flight: next-generation flow cytometry for multiplexed single cell analysisFrom1 May 2018 → 30 Apr 2022Funding: FWO Medium Size Research Infrastructure
- Harnessing the intrinsic metabolism of CD8+ T cells to improve their anti-tumor immune responseFrom5 Feb 2018 → 31 Oct 2023Funding: FWO Strategic Basic Research Grant, Foundations, funds and other with scientific goal
- MATATUM: Validation and druggability development of macrophage-specific targets in the tumor microenvironment.From1 Jan 2018 → 31 Dec 2021Funding: FWO Strategic Basic Research (SBO)
Publications
1 - 10 of 314
- Evolution of the Experimental Models of Cholangiocarcinoma(2020)
Authors: Chiara Varamo
- Insulin potentiates FcepsilonRI-mediated signaling in mouse bone marrow-derived mast cells(2010)
Authors: Mario di Matteo
Pages: 1039 - 1046 - In vivo antitumoral efficacy of PhAc-ALGP-doxorubicin, an enzyme-activated doxorubicin prodrug, in patient-derived soft tissue sarcoma xenograft models(2017)
Authors: Jasmien Cornillie, Agnieszka Wozniak, Peter Pokreisz, Andrea Casazza, Yemarshet Kelemework Gebreyohannes, Maria Debiec-Rychter, Raf Sciot, Daphne Hompes, Patrick Schöffski
Pages: 1566 - 1575 - microRNAs in ES Cell Differentiation(2012)
Authors: Emanuele Berardi, Lieven Thorrez, Maurilio Sampaolesi
Pages: H931 - H939 - Podoplanin-Expressing Macrophages (PoEMs) Promote Lymphangiogenesis and Lymphoinvasion in Breast Cancer(2019)
Authors: Pawel Jacek Bieniasz-Krzywiec, Max Mazzone
- PRO-INVASIVE TUMOUR-STROMA INTERACTIONS: ROLE OF THE SECRETED OXIDOREDUCTASE CLIC3(2019)
Authors: Juan R Hernandez-Fernaud, Elena Ruengeler, Lisa J Neilson, Shehab Ismail, Iain McNeish, Samuel Atkinson, Sergio Lilla, Alice Santi, Stella M Valenzuela, Karen Blyth, et al.
Pages: 136 - 136 - Hypoxic cancer-associated fibroblasts increase NCBP2-AS2/HIAR to promote endothelial sprouting through enhanced VEGF signaling(2019)
Authors: Shehab Ismail Mohamed, Max Mazzone
- Identification of a chronic non-neurodegenerative microglia activation state in a mouse model of peroxisomal β-oxidation deficiency(2015)
Authors: Simon Verheijden, Lien Beckers, Andrea Casazza, Oleg Butovsky, Max Mazzone, Myriam Baes
Pages: 1606 - 20 - Tumor stroma: a complexity dictated by the hypoxic tumor microenvironment(2014)
Authors: Andrea Casazza, Giusy Di Conza, Mathias Wenes, Veronica Finisguerra, Sofie Deschoemaeker, Max Mazzone
Pages: 1743 - 1754 - Tumour growth inhibition and anti-metastatic activity of a mutated furin-resistant Semaphorin 3E isoform(2012)
Authors: Andrea Casazza, Max Mazzone
Pages: 234 - 50