Organisation
Laboratory of Translational Genetics (VIB-KU Leuven)
Division
The overall aim of the research of the Laboratory of Translational Genetics, is to unravel the genetic predisposition to cancer and to annotate somatic changes in solid tumors with the ultimate aim to discover and functionally validate genetic biomarkers for cancer therapies.
Projects
61 - 70 of 72
- Genetic biomarkers for anti-angiogenic therapies - a translational approach.From1 Jan 2011 → 31 Dec 2013Funding: Private funding of national origin - undefined
- SymBioSys: from variome to phenome.From1 Nov 2010 → 31 Oct 2018Funding: BOF - Concerted Research Project from 1994
- A pipeline for the analysis of full cancer genomes.From1 Oct 2010 → 15 Feb 2012Funding: FWO fellowships
- Breast cancer-associated risks of established susceptibility loci in other cancers.From27 Sep 2010 → 19 Nov 2015Funding: FWO fellowships, FWO research grant KAN
- Technical research platform & heavy equipment HiSeq200 (including CBOT computing system and warranty).From1 Sep 2010 → 31 Aug 2013Funding: Other federal scientific institutions
- Unraveling the common genetic basis for COPD, emphysema and lung cancer.From1 Aug 2010 → 16 Dec 2015Funding: Private funding of national origin - undefined, FWO fellowships
- Discovering novel somatic alterations in cancer using a full genome sequencing approach.From1 Jan 2010 → 31 Dec 2012Funding: FWO research grant KAN
- Single-cell profiling of tumor micro-environment dynamics during checkpoint immunotherapy.From1 Oct 2009 → TodayFunding: BOF - ZAP BOF mandates
- Somatic mutations and copy number alterations as prognostic markers for primary endometrial cancerFrom15 Jul 2009 → 26 Jun 2013Funding: Own budget, for example: patrimony, inscription fees, gifts
- Genetic variations predicting outcome in patients with acute coronary syndrome: next step towards a personalized medicine.From1 Jan 2009 → 31 Dec 2011Funding: FWO research grant KAN
Publications
1 - 10 of 668
- Locus-specific induction of gene expression from heterochromatin loci during cellular senescence(2022)
Authors: Dóra Bihary
Pages: 31 - + - Dysphagia during glucocorticoid treatment of dermatomyositis: a differential diagnostic challenge(2018)
Authors: Pierre Van Mol, Ellen De Langhe, Patrick Verschueren
- Association of genetic susceptibility variants for type 2 diabetes with breast cancer risk in women of European ancestry(2016)
Authors: Patrick Neven, Hui Zhao
Pages: 679 - 693 - A theoretical and matrix-isolation FT-IR investigation of the conformational landscape of N-acetylcysteine(2010)
Authors: Bram Boeckx, Guido Maes
Pages: 73 - 81 - Capmatinib for the treatment of non-small cell lung cancer(2019)
Authors: Johan Vansteenkiste, Els Wauters, Pierre Van Mol
Pages: 659 - 671 - Increased IL-10-producing regulatory T cells are characteristic of severe cases of COVID-19(2020)
Authors: Julika Neumann, Lore Vanderbeke, Margaux Gerbaux, Pierre Van Mol, Yannick Van Herck, Joost Wauters, Els Wauters, Adrian Liston, Stephanie Humblet-Baron
- SNPeffect 4.0: on-line prediction of molecular and structural effects of protein-coding variants(2012)
Authors: Greet De Baets, Joost Van Durme, Joke Reumers, Joost Schymkowitz, Frederic Rousseau
Pages: D935 - D939 - Subsequent Event Risk in Individuals With Established Coronary Heart Disease Design and Rationale of the GENIUS-CHD Consortium(2019)
Authors: Bram Boeckx, Frans Van de Werf, Els Wauters, Diether Lambrechts
- Genetic Predisposition Scores Associate with Muscular Strength, Size, and Trainability(2013)
Authors: Tom Thomaes, Martine Thomis, Steven Onkelinx, Kaatje Goetschalckx, Robert Fagard, Diether Lambrechts, Luc Vanhees
Pages: 1451 - 1459 - The diagnostic value of next generation sequencing in familial nonsyndromic congenital heart defects(2015)
Authors: Yaojuan Jia, Jacoba J Louw, Jeroen Breckpot, Bert Callewaert, Catherine Barrea, Yves Sznajer, Erika Souche, Luc Dehaspe, Joris Vermeesch, Diether Lambrechts, et al.
Pages: 1822 - 9