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Organisation

Laboratory for the Research of Neurodegenerative Diseases (VIB-KU Leuven Center for Brain & Disease Research)

Lab

Lifecycle:1 Jan 2006  →  Today
Organisation profile:

The Laboratory for the Research of Neurodegenerative Diseases performes research into the fundamental molecular processes that underlay neurodegenerative diseases such as Alzheimer’s and Parkinson’s. Their work has also contributed to insights into general physiologically mechanisms, in particular, the understanding of regulated intramembrane proteolysis as an important signaling mechanism in health and disease. They have demonstrated the role of regulated intramembrane proteolysis in Notch signaling via PS, in the regulation of apoptosis via PARL and in psychiatric neurodevelopmental disorder via Neuregulin cleavage by Aph1B γ-Secretase.

Keywords:diseases
Disciplines:Neurosciences, Biological and physiological psychology, Cognitive science and intelligent systems, Developmental psychology and ageing