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Organisation

Laboratory of Membrane Trafficking (VIB-KU Leuven Center for Brain & Disease Research)

Lab

Lifecycle:1 Jan 2006 →  Today
Organisation profile:

The research in the Laboratory of Membrane Trafficking  is focused on the cell biology and trafficking of the g-secretase components. This multiprotein complex has been implicated in a new signal transduction paradigm, called Regulated Intramembrane Proteolysis or RIP and is critical in a wide variety of important cellular activities including embryogenesis, brain development and haematopoiesis. RIP also plays a central role in Alzheimer's disease as it mediates the final step in the release of amyloid b from the amyloid precursor protein (APP).

Keywords:physiology
Disciplines:Laboratory medicine, Palliative care and end-of-life care, Regenerative medicine, Other basic sciences, Other health sciences, Nursing, Other paramedical sciences, Other translational sciences, Other medical and health sciences