Organisation
Laboratory of Computational Biology (VIB-KU Leuven)
Division
Research in the Laboratory of Computational Biology is focusing on gene and genome regulation, with applications in Drosophila and cancer, and on integrative genomics, developing computational methods for genomic data integration and analysis of next-generation sequence data.
Current researchers
11 - 20 of 21 results
- Eren Can Eksi (Member)
- Nikolai Hecker (Member)
- Jasper Janssens (Member)
- Niklas Kempynck (Member)
- Vasilis Konstantakos (Member)
- David Mauduit (Member)
- Alexandra Pančíková (Member)
- Gabriele Partel (Member)
- Olga Sigalova (Member)
- Ibrahim Ihsan Taskiran (Member)
Projects
11 - 20 of 64
- A whole-organism approach to uncover gene regulatory mechanisms in Drosophila melanogaster: towards a regulatory map at single-cell resolutionFrom1 Oct 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Mapping gene regulatory networks in the era of single-cell multi-omicsFrom1 Sep 2022 → TodayFunding: BOF - doctoral mandates
- Modeling gene regulation through end-to-end deep learning for expression predictionFrom1 Sep 2022 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Integration of long read genome sequencing and single-cell multi-omics to identify genetic variation underlying Parkinson’s diseaseFrom1 Sep 2022 → TodayFunding: BOF - doctoral mandates
- Rebus EsperFrom29 Jun 2022 → TodayFunding: Other federal scientific institutions
- Advanced infrastructure for fabrication of next-generation micro- and nanosystemsFrom1 May 2022 → TodayFunding: FWO Medium Size Research Infrastructure
- Cell-cell cOmmuNicaTion As a driver of Cancer cell state identiTy - Decoding the impact of cell-cell communications on the identity of tumor states in skin cancersFrom1 Jan 2022 → TodayFunding: FWO EOS
- Unravelling the regulatory code orchestrating neural circuit formationFrom5 Oct 2021 → TodayFunding: Own budget, for example: patrimony, inscription fees, gifts
- Deciphering the evolution of gene regulatory networks and enhancer architectures in neuronal cell types using single-cell deep learning and comparative genomicsFrom1 Oct 2021 → TodayFunding: FWO senior postdoctoral fellowship
- OncoAI - a machine-learning framework to predict cancer cell vulnerability at the gene-regulatory levelFrom1 Mar 2021 → TodayFunding: Foundations, funds and other with scientific goal
Publications
1 - 10 of 177
- Identification of Circulating Fibrocytes and Dendritic Derivatives in Corneal Endothelium of Patients With Fuchs' Dystrophy(2017)
Authors: An-Katrien De Roo, Jasper Wouters, Olivier Govaere, Beatrijs Foets, Joost van den Oord
Pages: 670 - 681 - CNKSR1 gene defect can cause syndromic autosomal recessive intellectual disability.(2018)
Authors: Ibrahim Ihsan Taskiran
Pages: 691 - 699 - Recurrent rearrangements of FOS and FOSB define osteoblastoma(2018)
Authors: Annelien Verfaillie, Jonas Demeulemeester, Peter Van Loo
- Gene losses in the common vampire bat illuminate molecular adaptations to blood feeding(2022)
Authors: Nikolai Hecker
- iRegulon: From a Gene List to a Gene Regulatory Network Using Large Motif and Track Collections(2014)
Authors: Annelien Verfaillie, Hana Imrichova, Bram Van de Sande, Laura Standaert, Marina Naval Sanchez, Delphine Potier, Dmitry Svetlichnyy, Zeynep Kalender Atak, Mark Fiers, Chris Marine, et al.
- Male-Specific Fruitless Isoforms Target Neurodevelopmental Genes to Specify a Sexually Dimorphic Nervous System(2014)
Authors: Bram Van de Sande, Stein Aerts
Pages: 229 - 241 - Decoding the regulatory landscape of melanoma reveals TEADS as regulators of the invasive cell state(2015)
Authors: Annelien Verfaillie, Hana Imrichova, Zeynep Kalender Atak, Michael Dewaele, Valerie Christiaens, Dmitry Svetlichnyy, Flavie Luciani, Laura Van den Mooter, Sofie Claerhout, Mark Fiers, et al.
- EXPLORING THE CODE OF LIFE: FROM DECODING TO DESIGNING CELL TYPE-SPECIFIC ENHANCERS WITH DEEP LEARNING(2023)
Authors: Ibrahim Ihsan Taskiran, Stein Aerts
- Adult interfollicular tumour-initiating cells are reprogrammed into an embryonic hair follicle progenitor-like fate during basal cell carcinoma initiation(2012)
Authors: Bram Van de Sande, Stein Aerts
Pages: 1282 - 1294 - Sequencing the regulatory genome(2008)
Authors: Stein Aerts