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Organisation
Laboratory for Biochemical Neuroendocrinology
Division
Main organisation:Department of Human Genetics
Lifecycle:1 Jan 2006 → Today
Organisation profile:
The Laboratory for Biochemical Neuroendocrinology conducts research into protein biosynthesis, maturation and trafficking in the (regulated) secretory pathway, in relation to human diseases like diabetes, obesity and autism.
Keywords:biochemical
Disciplines:Biochemistry and metabolism, Medical biochemistry and metabolism
Current researchers
1 - 3 of 3 results
- John Creemers (Responsible)
- Ilaria Coppola (Member)
- Yenthe Monnens (Member)
Projects
1 - 10 of 11
- Unraveling the pathology of the novel congenital myasthenic syndrome-22 (CMS22) and investigation of molecular links with Prader-Willi syndrome.From1 Oct 2021 → TodayFunding: FWO Strategic Basic Research Grant
- The role of the proprotein convertases in diabetes and obesityFrom1 Sep 2016 → 12 Jul 2022Funding: FWO fellowships
- Functional characterization of PREPL and the role in Prader-Willi syndromeFrom1 Jan 2015 → 13 Dec 2021Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of the proprotein convertase furin in cancerFrom22 Sep 2014 → 3 Aug 2020Funding: Own budget, for example: patrimony, inscription fees, gifts
- The role of PREPL in regulated secretion and neuromuscular transmission.From21 Aug 2011 → 14 Sep 2014Funding: FWO fellowships
- (ATHEROGAG) Macrophage proteoglycans in atherosclerosis.From1 Jul 2011 → 15 Jun 2015Funding: Marie Curie - People
- Characterization of the regulated secretory pathway in neurons of a mouse model for autism.From1 Oct 2010 → 21 Mar 2016Funding: Private funding of national origin - undefined, FWO fellowships
- The role of furin in beta cell proliferation.From1 Aug 2009 → 19 Nov 2015Funding: IWT personal funding - strategic basic research grants
- Hyperplasia of the islets of Langerhans in transgenic mice with targeted PLAG1 overexpression in the pancreas.From1 Jan 2009 → 31 Dec 2011Funding: FWO research grant KAN
- The role of PREPL in hypotonia-cystinuria syndromeFrom8 Sep 2008 → 31 Dec 2019Funding: Own budget, for example: patrimony, inscription fees, gifts
Publications
1 - 10 of 82
- Novel Infantile-Onset Leukoencephalopathy With High Lactate Level and Slow Improvement(2012)
Authors: Luc Régal
Pages: 718 - 722 - Inactivation of the LRP1 intracellular NPxYxxL motif in LDLR-deficient mice enhances postprandial dyslipidemia and atherosclerosis(2009)
Authors: Philip Gordts, Amber Van Dongen, Anton Roebroek
Pages: 1258 - 1264 - Opposing effects of apoM on catabolism of apoB-containing lipoproteins and atherosclerosis(2010)
Authors: Christina Christoffersen, Tanja Xenia Pedersen, Philip Gordts, Anton Roebroek, Björn Dahlbäck, Lars Bo Nielsen
Pages: 1624 - 1634 - [Newborn screening : the point of view of the paediatrician].(2015)
Authors: Luc Régal
Pages: 212 - 218 - Functional characterization of Neurobeachin/rugose, a candidate gene for autism(2010)
Authors: Karolien Volders, Patrick Callaerts, John Creemers
Pages: 60 - 60 - Opposing Effects of Apolipoprotein M on Catabolism of Apolipoprotein B-Containing Lipoproteins and Atherosclerosis(2010)
Authors: Philip Gordts, Anton Roebroek
Pages: 1624 - 1634 - Clinical and biochemical features of aromatic L-amino acid decarboxylase deficiency(2010)
Authors: Luc Régal
Pages: 64 - 71 - Posttranslational processing of FGF23 in osteocytes during the osteoblast to osteocyte transition(2016)
Authors: Bruno Ramos Molina
Pages: 120 - 130 - PCSK1 mutations and human endocrinopathies: from obesity to gastrointestinal disorders(2016)
Authors: Pieter Stijnen, Bruno Ramos Molina, John Creemers
Pages: 347 - 371 - The Dwarf Phenotype in GH240B Mice, Haploinsufficient for the Autism Candidate Gene Neurobeachin, Is Caused by Ectopic Expression of Recombinant Human Growth Hormone(2014)
Authors: Krizia Tuand, Pieter Stijnen, Hugo Vankelecom, John Creemers