Organisation
Intellectual Property
Administrative Office
Projects
11 - 16 of 16
- Targeting the chromatin for innovative cancer therapy.From1 Nov 2014 → 31 Oct 2018Funding: SBO (Strategic basic research)
- Nuclear-cytoplasmic transport as novel therapeutic target.From1 Oct 2014 → 30 Sep 2018Funding: IOF - Industrial Research Fund
- Development of novel selective ghrelin O-acyltransferase inhibitors for the treatment of obesity and obesity-related type 2 diabetesFrom1 Apr 2014 → 31 Mar 2015Funding: IOF - Industrial Research Fund
- Validation of small molecule inhibitors of MALT1 protease for the treatment of auto-immune disorders and NF-κB-addicted lymphomas.From1 Oct 2013 → 30 Sep 2014Funding: IOF - Industrial Research Fund
- Evaluation of the (in vivo) efficacy of a novel class of broad-spectrum fungicidal compounds.From1 Jun 2009 → 31 May 2010Funding: IOF - Industrial Research Fund
- CD3 - the Centre for Drug Design and Discovery – discovering new drugs based on innovative researchFrom1 Oct 2006 → TodayFunding: IOF - Industrial Research Fund, IOF - mandates
Publications
1 - 10 of 44
- Synthesis and pharmacological evaluation of carboxycoumarins as a new antitumor treatment targeting lactate transport in cancer cells(2013)
Authors: Nihed Draoui, Patrick Chaltin
Pages: 7107 - 7117 - TRPM3-A promising target for analgesic treatment(2014)
Authors: Kathi Held, Patrick Chaltin, Thomas Voets, Joris Vriens
Pages: 98 - 98 - LEDGINs, non-catalytic site inhibitors of HIV-1 integrase: a patent review (2006 - 2014)(2014)
Authors: Jonas Demeulemeester, Patrick Chaltin, Arnaud Marchand, Marc De Maeyer, Zeger Debyser, Frauke Christ
Pages: 609 - 632 - Stimulation of the atypical chemokine receptor 3 (ACKR3) by a small-molecule agonist attenuates fibrosis in a preclinical liver but not lung injury model(2022)
Authors: Tom Van Loy, Steven De Jonghe, Wouter Dheedene, Patrick Chaltin, Aernout Luttun, Dominique Schols
- Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery(2020)
Authors: Rana Abdelnabi, Kim Donckers, Pieter Leyssen, Patrick Chaltin, Johan Neyts, Leen Delang
- Discovery of a new Mycobacterium tuberculosis thymidylate synthase X inhibitor with a unique inhibition profile(2017)
Authors: Rania Abou El Asrar, Arnaud Marchand, Patrick Chaltin, Steven De Jonghe, Piet Herdewyn, Eveline Lescrinier
Pages: 69 - 78 - Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects(2018)
Authors: Nihed Draoui, Patrick Chaltin
- Dual inhibition of SARS-CoV-2 and human rhinovirus with protease inhibitors in clinical development(2021)
Authors: Patrick Chaltin
- TRPM3-A Promising Target for Analgesic Treatment(2014)
Authors: Kathi Held, Silvia Joao Pinto, Sara Kerselaers, Katrien De Clercq, Patrick Chaltin, Thomas Voets, Joris Vriens
Pages: 754 - Small molecule inhibitors of the LEDGF/p75 binding site of integrase (LEDGINs) block HIV replication and modulate integrase multimerization(2012)
Authors: Frauke Christ, Jonas Demeulemeester, Belete Ayele Desimmie, Arnaud Marchand, Wim Smets, Patrick Chaltin, Zeger Debyser
Pages: 4365 - 4374