Organisation
Intellectual Property
Administrative Office
Current researchers
1 - 1 of 1 results
- Patrick Chaltin (Member)
Projects
1 - 9 of 9 results
- MATATUM: Validation and druggability development of macrophage-specific targets in the tumor microenvironment.From1 Jan 2018 → TodayFunding: FWO Strategic Basic Research (SBO)
- Targeting ZEB pathways to tackle aggressive (colorectal) cancer (ZENTACC).From1 Jan 2018 → TodayFunding: FWO Strategic Basic Research (SBO)
- Towards a combined post-exposure prophylaxis and successful treatment of rabies in humansFrom1 Oct 2017 → 30 Sep 2020Funding: FWO research project
- iKap: Targeting nucleocytoplasmic transport for novel anti-cancer therapy.From1 Oct 2015 → 30 Nov 2019Funding: SBO (Strategic basic research)
- Targeting the chromatin for innovative cancer therapy.From1 Nov 2014 → 31 Oct 2018Funding: SBO (Strategic basic research)
- Nuclear-cytoplasmic transport as novel therapeutic target.From1 Oct 2014 → 30 Sep 2018
- Development of novel selective ghrelin O-acyltransferase inhibitors for the treatment of obesity and obesity-related type 2 diabetesFrom1 Apr 2014 → 31 Mar 2015Funding: IOF - Industrial Research Fund
- Validation of small molecule inhibitors of MALT1 protease for the treatment of auto-immune disorders and NF-κB-addicted lymphomas.From1 Oct 2013 → 30 Sep 2014Funding: IOF - Industrial Research Fund
- Evaluation of the (in vivo) efficacy of a novel class of broad-spectrum fungicidal compounds.From1 Jun 2009 → 31 May 2010Funding: IOF - Industrial Research Fund
Publications
1 - 10 of 38 results
- Novel Class of Chikungunya Virus Small Molecule Inhibitors That Targets the Viral Capping Machinery(2020)
Authors: Rana Abdelnabi, Kristina Kovacikova, Julia Moesslacher, Kim Donckers, Verena Battisti, Pieter Leyssen, Thierry Langer, Gerhard Puerstinger, Gilles Querat, Changqing Li, et al.
Number of pages: 11 - Functional expression and pharmacological modulation of TRPM3 in human sensory neurons(2020)
Authors: Laura Vangeel, Melissa Benoit, Yannick Miron, Paul E Miller, Katrien De Clercq, Patrick Chaltin, Catherine Verfaillie, Joris Vriens, Thomas Voets
Pages: 2683 - 2695Number of pages: 13 - Discovery of Indole Derivatives as Novel and Potent Dengue Virus Inhibitors(2018)
Authors: Dorothee Bardiot, Mohamed Koukni, Wim Smets, Gunter Carlens, Michael McNaughton, Suzanne Kaptein, Kai Henrik Dallmeier, Patrick Chaltin, Johan Neyts, Arnaud Marchand
Pages: 8390 - 8401Number of pages: 12 - Modifying Rap1-signalling by targeting Pde6 delta is neuroprotective in models of Alzheimer's disease(2018)
Authors: Michael Dumbacher, Tom Van Dooren, Katrien Princen, Koen De Witte, Melissa Farinelli, Sam Lievens, Jan Tavernier, Wim Dehaen, Stefaan Wera, Joris Winderickx, et al.
Number of pages: 21 - Differential antiviral activities of respiratory syncytial virus (RSV) inhibitors in human airway epithelium(2018)
Authors: Carmen Mirabelli, Martine Jaspers, Mieke Boon, Mark Jorissen, Mohamed Koukni, Dorothee Bardiot, Patrick Chaltin, Arnaud Marchand, Johan Neyts, Dirk Jochmans
Pages: 1823 - 1829Number of pages: 7 - Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects(2018)
Authors: Cyril Corbet, Estelle Bastien, Nihed Draoui, Bastien Doix, Lionel Mignion, Benedicte F Jordan, Arnaud Marchand, Jean-Christophe Vanherck, Patrick Chaltin, Olivier Schakman, et al.
Number of pages: 11 - 1-((2,4-Dichlorophenethyl)Amino)3-Phenoxypropan-2-ol Kills Pseudomonas aeruginosa through Extensive Membrane Damage(2018)
Authors: Valerie Defraine, Veerle Liebens, Evelien Loos, Toon Swings, Bram Weytjens, Carolina Fierro, Kathleen Marchal, Liam Sharkey, Alex J O'Neill, Romu Corbau, et al.
Number of pages: 13 - An allosteric binding site of the alpha 7 nicotinic acetylcholine receptor revealed in a humanized acetylcholine-binding protein(2018)
Authors: Florian Delbart, Marijke Brams, Fabian Gruss, Samuel Noppen, Steve Peigneur, Sandro Boland, Patrick Chaltin, Jose Brandao-Neto, Frank von Delft, Wouter G Touw, et al.
Pages: 2534 - 2545 - Antibacterial Activity of 1-[(2,4-Dichlorophenethyl)amino]-3-Phenoxypropan-2-ol against Antibiotic-Resistant Strains of Diverse Bacterial Pathogens, Biofilms and in Pre-clinical Infection Models(2017)
Authors: Valerie Defraine, Laure Verstraete, Françoise Van Bambeke, Ahalieyah Anantharajah, Eleanor Townsend, Gordon Ramage, Romu Corbau, Arnaud Marchand, Patrick Chaltin, Maarten Fauvart, et al.
Pages: 2585 - Identification of 1-((2,4-Dichlorophenethyl)Amino)-3-Phenoxypropan-2-ol, a Novel Antibacterial Compound Active against Persisters of Pseudomonas aeruginosa(2017)
Authors: Veerle Liebens, Valerie Defraine, Wouter Knapen, Toon Swings, Serge Beullens, Romu Corbau, Arnaud Marchand, Patrick Chaltin, Maarten Fauvart, Jan Michiels
Number of pages: 13