Organisation
Department of Oncology
Department
The Department of Oncology at the KU Leuven fosters synergy in innovative oncological research. By creating a close link between bed and bench and by capitalizing on advanced technologies, our researchers aim to unravel key molecular mechanisms underlying the development and progression of cancer and to maximize opportunities to translate these findings into better clinical biomarkers, adaptive strategies and innovative treatments
Sub-organisation(s)
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- Abdominal Surgical Oncology
- Laboratory of Intravital Microscopy and Dynamics of Tumor Progression (VIB-KU Leuven)
- Pediatric Oncology
- Metabolomics Expertise Center (VIB-KU Leuven)
- Laboratory for Translational Breast Cancer Research
- Laboratory of Cellular Metabolism and Metabolic Regulation (VIB-KU Leuven)
- Laboratory of Experimental Hematology
- Laboratory of Experimental Oncology
- Gynaecological Oncology
- Laboratory for Mechanisms of Cell Transformation (VIB-KU Leuven)
Current researchers
1 - 6 of 6 results
- Baki Topal (Responsible)
- Ewout Landeloos (Member)
- Evy Lobbestael (Member)
- Pavlo Lutsik (Member)
- sahar Motamedi (Member)
- Sophie Vlayen (Member)
Projects
1 - 6 of 6
- Ph.D. in computational methods for cancer multi-omicsFrom13 Jan 2023 → TodayFunding: BOF - doctoral mandates
- Approaching personalized oncology with DNA methylation inference and computational epigenomicsFrom1 Oct 2022 → TodayFunding: BOF - ZAP BOF mandates
- PROMICE: Advancing Precision Oncology via Methylome Inference and Computational EpigenomicsFrom1 Oct 2022 → TodayFunding: BOF - projects
- Unravelling the mechanisms of drug resistance to proteasome inhibitors to optimize treatment in patients with multiple myelomaFrom10 Sep 2018 → 31 Oct 2023Funding: FWO Strategic Basic Research Grant
- Characterisation of LRRK2 kinase function in a-synuclein-induced neurotoxicity and neuroinflammation.From7 Sep 2017 → 31 Oct 2023Funding: FWO fellowships
- Study of pro-survival effects of increased lipogenesis in cancer cells: implications for carcinogenesis and therapy.From1 Oct 2009 → 18 Nov 2014Funding: FWO fellowships
Publications
21 - 30 of 148
- Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer(2015)
Authors: Diether Lambrechts, Sandrina Lambrechts, Els Van Nieuwenhuysen, Ignace Vergote
Pages: 8234 - GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer(2013)
Authors: Diether Lambrechts, Sandrina Lambrechts, Ignace Vergote
Pages: 362 - 70 - A cellular hierarchy in melanoma uncouples growth and metastasis (vol 610, pg 190, 2022)(2022)
Authors: Panagiotis Karras, Joanna Poźniak, Nina Van Raemdonck, Ewout Landeloos, Yannick Van Herck, Michael Dewaele, Yichao Hua, Gabriele Bergers, Francesca Bosisio, Joost van den Oord, et al.
Pages: E4 - E4 - No clinical utility of KRAS variant rs61764370 for ovarian or breast cancer(2016)
Authors: Breast Cancer Association Consortium, and Consortium of Modi Ovarian Cancer Association Consortium, Antoinette Hollestelle, Frederieke H van der Baan, Andrew Berchuck, Sharon E Johnatty, Katja K Aben, Bjarni A Agnarsson, Kristiina Aittomäki, Elisa Alducci, Irene L Andrulis, et al.
Pages: 386 - 401 - Analysis of Over 10,000 Cases Finds No Association between Previously-Reported Candidate Polymorphisms and Ovarian Cancer Outcome(2013)
Authors: Diether Lambrechts, Sandrina Lambrechts, Ignace Vergote
Pages: 987 - 92 - Shared heritability and functional enrichment across six solid cancers (vol 10, 431, 2019)(2019)
Authors: Xia Jiang, Hilary K Finucane, Fredrick R Schumacher, Stephanie L Schmit, Jonathan P Tyrer, Younghun Han, Kyriaki Michailidou, Corina Lesseur, Karoline B Kuchenbaecker, Joe Dennis, et al.
- Genetic heterogeneity after first-line chemotherapy in high-grade serous ovarian cancer(2015)
Authors: Sandrina Lambrechts, Dominiek Smeets, Matthieu Moisse, Adriaan Vanderstichele, Hui Zhao, Els Van Nieuwenhuysen, Diether Lambrechts, Ignace Vergote
Pages: 51 - 64 - itraconazole for COVID-19: Preclinical studies and a proof-of-concept randomized clinical trial Laurens (vol 66, 103288, 2021)(2021)
Authors: Laurens Liesenborghs, Dirk Jochmans, Ann Belmans, Iwein Gyselinck, Sebastiaan ter Horst, Erwin Dreesen, Tatjana Geukens, Ewout Landeloos, Bert Vandenberk, Lorenz Van der Linden, et al.
- An Experimental 2D Computed Radiography (CR) Dosimeter for IMRT. Are In-Field Measurements Affected by the Low Energy Photon Overresponse?(2016)
Authors: Wouter Crijns, D Vandenbroucke, P Leblans, T Depuydt
Pages: 3531 - 3531 - Commissioning of a Pre-Configured Fast-Rotating O-Ring Gantry Linac System and IMRT/VMAT Treatment Delivery Quality(2018)
Authors: R De Roover, K Poels, Wouter Crijns, A Nulens, B Vanstraelen, K Haustermans, T Depuydt
Pages: E525 - E526