Using mucins as friends in colorectal cancer diagnostics and treatment

Education 2019.09-2022.07 The Sixth Affiliated Hospital, Sun Yat-sen University    Major: General Surgery    Mentor: Prof. Xianrui Wu (Professor, Colorectal Surgery) 2014.08-2019.07 Zhongshan School of Medicine, Sun Yat-sen University    Major: Clinical Medicine Researches: 2019.09-2022.09 Direction 1: The immune microenvironment and methylation level of colorectal cancer (CRC) for its development and metastasis    Abstract: Focusing on the sensitization of immune checkpoint treatments for MSI-L/MSS CRC. Various mouse models have been proficiently constructed，like subcutaneous tumor, orthotopic and lung metastasis, CD8 depletion models;CD8+ T cell separation, activation, migration experiments; Peripheral blood    methylation level detection and data analysis. Direction 2: The impact of staging on the short-term and long-term complications of postoperative colorectal cancer patients Abstract: Focusing on the incidence of complications in CRC patients in different stages and different stages after surgery, especially on the impact of the pelvic meridian. 2016.07-2016-09 Short-term research《 Study on the restricted presentation of CD277+ CD14+ monocyte-macrophages in γδ T cell recognition and binding of phosphorylated antigen 》 Pubulished articles 2022.09.07 Wu Q* Yue X* Liu H*, et al. MAP7D2 reduces CD8+ cytotoxic T lymphocyte infiltration through MYH9-HMGB1 axis in colorectal cancer. Molecular Therapy. 2021.04.23 Zhang Y*, Wu Q*, Xu L, et al. Sensitive detection of colorectal cancer in peripheral blood by a novel methylation assay. Clinical Epigenetics. Awards & Skills 2019-2021,Scholarship and bursary of Sun Yat-sen University; 2015-2016，Personal Excellence Award of Sun Yat-sen University Alumni Association; Professional with Office , SPSS, R language, AI/PS and other research software Clinical Experience 2018.12-2019.05 Internship in Sun Yat-sen Memorial Hospital of Sun Yat-sen University 2018.05-2018.12 Internship in Shantou Central Hospital Affiliated Shantou Hospital of Sun Yat-sen University 2017.10-2018.05 Internship in the First Affiliated Hospital of Sun Yat-sen University