Targeting and in vivo imaging of tumor-associated macrophages

The disclosure relates to activities and characteristics of tumor-associated macrophages (TAMs). In particular, immunoglobulin single variable domains are provided against markers of TAMs, and methods using the same for in vivo imaging of tumor cells, as well as cancer diagnostics and therapeutics.

Patent Publication Number: US9913920

Year filing: 2018

Year approval: 2018

Validated for IOF-key: Yes

Attributed to: Universitaire Associatie Brussel