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Project
The interactions between sex steroids, bone geometry and body composition in transsexual
Context
Therapy of gender identity disorder induces an altered hormonal milieu.
Design
Prospective intervention study in 100 transsexuals,
cross-sectional study after long-term therapy in 50 female-to-male transsexuals
Objective
To explore the interplay of bone, fat, steroids and metabolism in relation to cross-sex hormonal therapy
Methods
Body composition and bone imaging, serum/tissue hormones, muscle/fat biopsies and mRNA expression of regulating factors
Date:1 Oct 2011 → 30 Sep 2014
Keywords:sex steroids, bone, body composition, gender identity disorder
Disciplines:Endocrinology and metabolic diseases, Orthopaedics