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Project
In depth insight into the translatome using state-of-the-art proteomics and ribosome profiling, applications on different in vitro model systems.
From a proteogenomic approach, bioinformatic tools will be developped to combine ribosome profiling and mass spectrometry results. These tools will secure exhaustive analysis of different translation features and controls. Experiments will be performed in cell lines and afterwards in embryoid and organoid bodies, as a proxy to in vivo tissue.
Date:1 Oct 2015 → 30 Sep 2019
Keywords:proteomics, organoid bodies, cell lines, translation control, ribosome profiling, mass spectrometry, bioinformatics, translation, proteogenomics, embryoid bodies
Disciplines:Scientific computing, Biomaterials engineering, Other biotechnology, bio-engineering and biosystem engineering, Genetics, Public health services, Morphological sciences, Information systems, Industrial biotechnology, Visual computing, Oncology, Animal biology, Public health care, Bioinformatics and computational biology, Information sciences, Distributed computing, Other information and computing sciences, Environmental engineering and biotechnology, Veterinary medicine, Computer architecture and networks, Theoretical computer science, Biological system engineering, Other (bio)medical engineering, Applied mathematics in specific fields, Programming languages, Biomechanical engineering