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Project
Analysis of chromosomal radiosensitivity/instability in triple negative and/or young breast cancer patients and patients with Fanconi anemia from South Africa
Chromosomal radiosensitivity has been observed in breast cancer patients in European populations and is linked with DNA repair pathways. As triple negative, young breast cancer and Fanconi anemia patients frequently have defects in these pathways , the chromosomal radiosensitivity, instability and the link with DNA repair genes will be investigated in these patients.
Date:1 Oct 2015 → 30 Sep 2019
Keywords:triple negative breast cancer, chromosomal radiosensitivity, young breast cancer, DNA repair, Fanconi anemia
Disciplines:Molecular and cell biology, Laboratory medicine, Plant biology, Systems biology, Medical systems biology, Medical imaging and therapy, Medicinal and biomolecular chemistry, Genetics, Biophysics