Combining optogenetics, chemogenetics, intracranial electroencephalography and functional magnetic resonance imaging to investigate abnormal functioning of brain networks during epileptogenesis

This project will investigate

1. how brain networks change during the development of epilepsy using functional MRI, specific neuromodulation tools and advanced network analysis;
2. whether epilepsy-related network changes are linked with the severity of epilepsy and the obtained efficacy of epilepsy therapies and
3. whether these network changes can be reversed in order to suppress epileptic seizures.