Towards the clinical application of total HIV DNA: a valuable marker for the diagnosis of HIV-infected infants and treatment follow-up in HIV adults.

We hypothesize HIV DNA as a valuable predictive and prognostic marker in clinical care of patients and as a sensitive marker for the early diagnosis of HIV-infected infants. A validated HIV DNA assay is needed that quantifies efficiently HIV DNA from various HIV subtypes , followed by the validation of the clinical relevance of total HIV DNA as a biomarker.