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Project
Study of the role of A20 (TNFAIP3) and RIPK4 in skin homeostasis and disease.
The skin constitutes a protective barrier and provides a well-balanced response against diverse insults from the environment. The existence of many skin pathologies, underscores the demand for a well-orchestrated keratinocyte differentiation program and for a tight control of skin homeostasis. We want to study the role of the ubiquitin-editing protein A20 and RIPK4 kinase in skin homeostatis, cancer and inflammation.
Date:1 Jan 2012 → 31 Dec 2014
Keywords:RIP kinases, skin, NF-kB, A20/TNFAIP3
Disciplines:Oncology, Dermatology, Morphological sciences