Improvement of memory function after Prophylactic Cranial Irradiation (PCI) by avoidance of the hippocampus

The consortium wants to perform a phase III randomized clinical trial to clinical validation of HA-PCI in patients with NSCLC. Moreover, the clinical validation of HA-PCI will give an impetus to the prophylactic irradiation of brain metastases from other cancer patients with a high risk of brain metastases, such as patients with locally advanced non-small cell lung cancer. high-risk breast cancer patients and patients with primary brain tumors.