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Project
Mode of action of house dust mite specific immunotherapy.
The proposed project aims to elucidate the mode of action of house dust mite specific immunotherapy. We will address this question in 2 different ways:
- Ex vivo: in peripheral blood and at local tissue level of patients undergoing HDM SIT.
- In vivo: in severe combined immunodeficiency mice reconstituted with peripheral blood mononuclear cells of patients undergoing HDM SIT.
Date:1 Oct 2013 → 30 Sep 2017
Keywords:Specific immunotherapy, Allergic airway inflammation, Humanized SCID mouse model, House dust mite
Disciplines:Other health sciences, Other translational sciences, Otorhinolaryngology, Speech, language and hearing sciences, Laboratory medicine, Immunology, Respiratory medicine, Regenerative medicine, Palliative care and end-of-life care, Other clinical sciences, Other basic sciences, Nursing, Other medical and health sciences, Other paramedical sciences