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Project

Distribution and transport of uremic retention solutes: from modelling towards optimisation of hemodialysis

Kinetic models for different retention solutes like the protein-bound solutes are calibrated and validated based on in vitro and in vivo data. These models are further used to develop a new parameter to indicate hemodialysis adequacy as well as to optimise and personalise the hemodialysis treatment.

Date:1 Jan 2014 →  31 Dec 2019
Keywords:uremic toxins, protein-bound, hemodialysis, dialysis adequacy, kinetics, solute distribution
Disciplines:Urology and nephrology