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Project
The formation of metastases is the main cause of cancer-related mortality
The formation of metastases is the main cause of cancer-related mortality (90%). Strikingly, no effective anti-metastatic therapy is available in the clinic yet. N-Cadherin (NCad) is a protein that is abnormally active in metastatic tumors and helps them spread. The current project aims at developing molecules which can block NCad in patients.
Date:1 Oct 2012 → 30 Sep 2018
Keywords:drug design, metastasis, cancer
Disciplines:Organic chemistry, Morphological sciences, Oncology, Other pharmaceutical sciences, Pharmacognosy and phytochemistry, Medicinal products, Pharmacology, Pharmaceutics, Toxicology and toxinology, Pharmacotherapy, Drug discovery and development, Biomarker discovery and evaluation