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Project
The role of folate in DNA methylation in plants.
Folates provide methylgroups to methyltransferases, which, in turn, enables them to methylate DNA (and other molecules). The role of folates in DNA methylation in Arabidopsis thaliana will be further investigated by studying folate biosynthesis mutants (dhfr) and folate biofortified plants. Furthermore, the nuclear fraction of the folate pool will be determined in the aforementioned lines.
Date:1 Oct 2014 → 30 Sep 2016
Keywords:folate, arabidopsis thaliana, epigenetics, DNA methylation, metabolic engineering
Disciplines:Biomechanical engineering, Plant biology, Other biotechnology, bio-engineering and biosystem engineering, Environmental engineering and biotechnology, Biological system engineering, Other (bio)medical engineering, General biology, Biomaterials engineering, Industrial biotechnology