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Project
Development of synthetic strategies for phosphono-isoindoles and related heterocyclic phosphonates
Recently a new methodology for the synhesis of 2-phosphonoisoindoles from x-aminophosphonates was developed at the department of organic chemistry of the faculty of bioscience engineering. The reaction comprises a 5-exo-dig cyclisation, a [1,3]-alkyl shift and spontaneous aromatisation. This project will develop this strategy towards the synthesis of new classes of heterocyclic phosphonates and analoguous heterocycles.
Date:1 Oct 2008 → 30 Sep 2012
Keywords:synthesis, phosphonates, organic chemistry
Disciplines:Organic chemistry