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Project
Method development for the characterization of serum/plasma protein glycosylation. Application in clinical hepatology, endocrinology, oncology and anti-doping control
This project aims to develop new methods for the characterisation of protein glycosylation patterns of serum proteins, and to apply these in clinical contexts. More specifically, sensitive and specific markers for liver cirrhosis and cancer are investigated, as is the influence of ageing on the glycosylation patterns of plasma hormones and hormone-binding proteins.
Date:1 Jan 2007 → 31 Oct 2011
Keywords:plasma steroids, liver cirrhosis, erythropoietin, tumor markers, protein glycosylation, glycomics
Disciplines:Biomechanical engineering, Gastro-enterology and hepatology, Endocrinology and metabolic diseases, Medicinal chemistry, Separation and membrane technologies, Biomaterials engineering, Industrial biotechnology, Laboratory medicine, Medical systems biology, Other (bio)chemical engineering, General chemical and biochemical engineering, Biological system engineering, Other biotechnology, bio-engineering and biosystem engineering, Chemical product design and formulation, Transport phenomena, Environmental engineering and biotechnology, Other (bio)medical engineering, Catalysis and reacting systems engineering, Process engineering