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Project
The role of dopamine D4 receptor ubiquitination and functional differences between the polymorphic variants.
The dopamine D4 receptor is a G protein- coupled receptor. We have shown that this receptor is ubiquitinated upon interaction with KLHL12 (a Kelch-BTB protein) and in this project we will investigate what the functional role of this receptor ubiquitination is.
Date:1 Jan 2009 → 31 Dec 2014
Keywords:ubiquitin, GPCR, dopamine
Disciplines:Neurosciences, Other biotechnology, bio-engineering and biosystem engineering, Biomaterials engineering, Medical biochemistry and metabolism, Biological system engineering, Other (bio)medical engineering, Industrial biotechnology, Biological and physiological psychology, Biochemistry and metabolism, Developmental psychology and ageing, Environmental engineering and biotechnology, Cognitive science and intelligent systems, Biomechanical engineering, Systems biology