Valorisation of LIPid waste by Thermophilic Yeasts for the production of long chain Dicarboxylic Acids (LIPTYDA).

In LIPTYDA we will create sustainable long-chain dicarboxylic acids (LCDAs) that are of great interest to several Flemish companies as they target different applications like high-grade polymers, plasticizers and lubricants. Current dicarboxylic acid production largely relies on fossil-based inputs and chemical processes, and is moreover limited to medium-chain products. In LIPTYDA we will focus on the novel long-chain dicarboxylic acids starting from grease trap waste (GTW); abundantly available in the food processing industry where it is collected during water treatment. GTW re-use is marginal as it is contaminated with food solids, and it is consequently mainly incinerated or deposited at landfills. Nevertheless, we see huge potential for GTW in biological fermentation processes: various LCDA producing yeast species thrive on lipids. First, we will thoroughly characterize the GTW and based on the outcome develop a suitable pretreatment. Next, we will apply advanced screening and synthetic biology approaches to obtain a yeast strain able to grow at high temperatures. Indeed, this is required to have GTW in the liquid state and guaranty good conversion to LCDAs. Finally, as we work with unusual temperatures and novel strains and feedstock, we will develop a new fermentation process using advanced reactor and cultivation technology.

Keywords:ORGANIC WASTE, INDUSTRIAL BIOTECHNOLOGY, LIPIDS

Disciplines:Lipids, Regulation of metabolism, Microbiology not elsewhere classified, Systems biology not elsewhere classified, Biocatalysis, Chemical kinetics and thermodynamics, Modelling, simulation and optimisation, Heat and mass transfer, Bioprocessing, bioproduction and bioproducts, Industrial microbiology, Industrial molecular engineering of nucleic acids and proteins

Project type:Collaboration project