Replication fork protector dependency factors: novel targets for combination treatment and immunomodulation in neuroblastoma (REINFORCE)

This study aims to identify and explore novel therapeutic targets for combination therapy and immunomodulation in neuroblastoma, a pediatric tumor of the developing peripheral nervous system. The teams will collaboratively apply novel technology in functional cancer genetics, oncoimmunology, animal modeling and liquid biopsy analysis. This program will yield novel therapeutic strategies with better survival and reduced adverse side effects.