Microbes-4-Immunity: single-cell based sorting and investigation of the functional microbiome in intestinal and extra-intestinal immune homeostasis.

The high incidence of chronic inflammatory and auto-immune disorders in a Western lifestyle is associated with the microbiome. It’s however extremely difficult to identify the functional microbiota, modulating immunodevelopment and -homeostasis. This project will generate new insights in microbehost interactions using a unique combination of flowcytometric cellsorting, access to clinical samples and an in vitro and in vivo technology platform.