Control of Nucleation and Crystallization of Oligopeptides in Flow (NuCryPept-control).

The NuCryPept-control project aims to create tools for the simplification of parameter-space exploration in the development of oligopeptide nucleation and crystallization. We are developing precise and accurate control technologies for various parameters in the crystallization process (pH, composition, concentration, temperature) that not only work on microscale, but in addition are scalable, so that the same technologies used for screening can also be applied in manufacturing to unburden, through crystallization, the purification process of biomacromolecules, which is currently expensive and inefficient.

Keywords:CRYSTALLIZATION, MICROFLUIDICS, PEPTIDES, NUCLEATIONS

Disciplines:Phase transformations, Flow chemistry, Separation technologies, Microfluidics/flow chemistry