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Project
Unraveling the Regenerative Potential of (Equine) Mesenchymal Stem Cells in a Representative in vitro Tendon Injury Model.
Equine tendon- and endothelial cells are combined with crosslinkable 3D-printable gelatin hydrogels to establish a representative tendinopathy model after mechanical stimulation. A first screening will be performed to identify metabolites and their pathways involved in tendon (patho-)physiology. Subsequently, the regenerative role of mesenchymal stem cell (MSC) versus fibroblast secretome on these metabolites and their pathways will be evaluated in vitro.
Date:1 Oct 2021 → 31 Oct 2021
Keywords:In vitro tendon injury model, Pathophysiological metabolic pathways, MSC secretome
Disciplines:Animal cell and molecular biology, Animal health engineering, Stem cell biology