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A metal-free heterogeneous photocatalyst for the selective oxidative cleavage of C=C bonds in aryl olefinsviaharvesting direct solar energy

Journal Contribution - Journal Article

Selective cleavage of C & xe001;C bonds is highly important for the synthesis of carbonyl containing fine chemicals and pharmaceuticals. Novel methodologies such as ozonolysis reactions, Lemieux-Johnson oxidation reactionetc. already exist. Parallel to these, catalytic methods using homogeneous catalysts also have been discovered. Considering the various advantages of heterogeneous catalysts such as recyclability and stability, couple of transition metal-based heterogeneous catalysts have been applied for this reaction. However, the pharmaceutical industries prefer to use metal-free catalysts (especially transition metal-free) to avoid further leaching in the final products. This is for sure a big challenge to an organic chemist and to the pharmaceutical industries! To make this feasible, a mild and efficient protocol has been developed using polymeric carbon nitrides (PCN) as metal-free heterogeneous photocatalysts to convert various olefins into the corresponding carbonyls. Later, this catalyst has been applied in the gram scale synthesis of pharmaceutical drugs using direct solar energy. Detailed mechanistic studies revealed the actual role of oxygen, the catalyst, and the light source.
Journal: Green chemistry : cutting-edge research for a greener sustainable future
ISSN: 1463-9262
Volume: 22
Pages: 4516 - 4522
Publication year:2020
Keywords:A1 Journal article
BOF-keylabel:yes
BOF-publication weight:3
CSS-citation score:3
Authors:International
Authors from:Higher Education
Accessibility:Open