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Project

Delivery of peptides, proteins and antibodies to the colon

The PhD is part of the COLOTAN project, funded by Marie Skłodowska-Curie Actions (MSCA) (grant agreement 956851). Aim of the PhD is the development of a formulation platform based on multiparticulate systems for the colon targeted delivery of biologics, including peptides, antibodies and proteins. Thus, the treatment of local gut diseases, mainly Crohn’s disease and irritable bowel syndrome (IBS) should be facilitated. The project includes the knowledge about the stabilization effect of GRAS material, the usage of different analytical tools for the characterization of biologics in both solid state and dissolution, and also the development of a colon-specific drug delivery system for biologics.

Date:7 Jun 2021 →  Today
Keywords:Drug delivery, Biologics, Colon targeting, Proteins, Peptides, Nucleic acids
Disciplines:Pharmaceutical technology
Project type:PhD project