Development of a technology platform for next-generation cytometry

Flow cytometry is a technique which has revolutionized cell-based scientific disciplines, including immunology, cancer and stem cell biology. The essence of flow cytometry is the ability to take a large mixed population of cells, narrow them down to a fluid stream that is only a single cell in diameter, and then read multiple parameters from that cell. This process allows us to distinguish different cell types apart from each other and to create pure populations for functional analysis. Flow cytometry is therefore both a critical technology in its own right, and also a gateway technology essential for any analysis that relies on purified cells.

In the current FACS Core, we provide access to flow cytometry to over 90 laboratories. The available machines need to be upgraded to solve multiple limitations. The requested equipment will allow us to sort clinical samples from potentially infected individuals, providing clinical research with access to this key technology platform. The new equipment will also transform the facility into one of the top cytometry services in the world, with access to advanced facilities currently not available in Belgium.