Getting a grip on slippery protein modifications in the immunopathology of multiple sclerosis (R-11585)

Instead of protecting us, the immune system sometimes goes awry, as in the case of the autoimmune disease multiple sclerosis. Previously, we demonstrated that lipids such as fatty acids are essential in driving the disease-promoting and –resolving properties of immune cells in multiple sclerosis. However, the molecular mechanisms involved remain poorly understood. In this study, we aim to unravel if binding of fats to proteins controls faulty immune cell function in multiple sclerosis, and explore whether that knowledge can be utilized for therapeutic purposes

Keywords:autoimmune desease, autoimmunity, immunology, multiple sclerosis

Disciplines:Autoimmunity