Automated slide scanner for digitalizing histopathology

To date, histological analysis remains the golden standard for tissue examination, for both qualitative and quantitative measurements, as it provides high resolution spatial information. However, storing section as static photomicrographs is still common practice and has major drawbacks. In this application, an automated slide scanner is requested as it allows for the generation of high-resolution virtual slides from complete specimens using both bright field and fluorescence imaging. It offers major advantages over the conventional method: (i) obtaining high quality digital images that provide high resolution at different magnifications and (ii) slides are stored as digital file that allows for easy retrieval, sharing, data management, remote inspection, and most importantly eliminate issues concerning fading of stains. The different research teams housed in the G-PURE lab generate a vast amount of histological sections on a daily basis and would greatly benefit from expanding its infrastructure with the whole image slide scanning technique.

Keywords:Histology, Chromogen, Fluorescence, Automation

Disciplines:Histology, Developmental biology