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Organisation

VIB CMN - Microglia and Inflammation in Neurological Disorders (MIND) lab

Research Group

Lifecycle:1 Oct 2020 →  Today
Organisation profile:Microglia and neuroinflammation play a central role in the pathogenesis of Alzheimer's disease and other neurodegenerative disorders. Our primary focus is to examine the underlying molecular mechanisms that drive Alzheimer's disease (AD) and Frontotemporal dementia (FTD), with special focus on inflammatory networks and particularly the contribution of microglia. We use mouse models, iPSC and cutting-edge humanised mouse systems to determine the immune component of these disorders and determine how genetics alter microglial function and contribute to the initiation and perpetuation of brain disease.
Keywords:STEM CELLS, TAU, ALZHEIMER'S DISEASE, NEUROLOGICAL DISORDERS, NEUROINFLAMMATION, NEURODEGENERATION, MICROGLIA
Disciplines:Immunology, Molecular and cell biology, Neurosciences