Morphological Uterus Sonographic Assessment (MUSA) project: Preoperative diagnosis of myometrial lesions using imaging (MUSA-1) and liquid biopsies (trans-MUSA).

Malignant myometrial lesions or sarcomas are highly aggressive and require radical surgery in an oncological centre. It is of utmost importance to accurately identify sarcomas, not only because any delay in diagnosis is associated with lower survival rates, but also because the inadvertent morcellation of a sarcoma may lead to diffuse intraabdominal spreading of malignant tissue and hence to a dramatic worsening of the patient’s prognosis. Our research group has ample experience in gynecological ultrasound as well as liquid biopsy research. The knowledge about sonographic and liquid biopsy biomarkers in malignant myometrial disease is low. Our research aims to define sonographic features and to identify new liquid biopsy biomarkers that enable to differentiate a sarcoma from a myoma.

Keywords:uterus, myometrium, sarcoma, myoma, ultr

Disciplines:Cancer diagnosis