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Project

Unraveling the molecular mechanisms underlying biological control of hairy root disease in tomato by Paenibacillus strains

'Hairy root disease' (HRD) (also known as 'crazy roots') is a plant disease in tomato, cucumber, and eggplant, which is caused by rhizogenic agrobacteria. HRD is characterized by extensive root proliferation, which ultimately leads to severe economic losses. HRD is a rapidly spreading and highly persistent disease, which is not easily managed with conventional biocides. The main aim of this project is to further optimize the use of bacteria biocontrol organisms (BCOs). Implementation of these BCOs should ultimately contribute to a sustainable and integrated pest management strategy. In previous research, we patented several bacterial strains showing antagonistic activity against rhizogenic agrobacteria. Preliminary experiments indicate that these biocontrol organisms (BCO's) show a huge potential to prevent or at least reduce infection with rhizogenic agrobacteria. Howerver, little is known about the mode of action and the optimal conditions for application in practice. A first major aim of this project is to gain deeper insight into the mode of action of the BCOs. The identification of the antagonisctic compound would be an important first step. Secondly, we want to investigate the optimal conditions for the use of the BCOs in practice. In that regard, we want to assess the optimal application method and determine in which conditions the BCO's can exert their antagonistic activity. Altogether, this project allows to take a major step towards commercialization of the BCOs.

Date:21 Sep 2020 →  15 Jan 2023
Keywords:Biocontrol, Hairy root disease, Rhizogenic agrobacteria, Biocontrol organisms
Disciplines:Phytopathology, Bacteriology, Infectious diseases, Genetics not elsewhere classified, Metabolomics
Project type:PhD project